Anion Gap Calculator (with Albumin Correction and Delta Ratio)

13 / Acid–Base

Anion Gap

Anion gap, albumin correction and delta ratio

AG = Na⁺ − (Cl⁻ + HCO₃⁻)

Laboratory Values

Sodium (Na⁺)
mEq/L
Chloride (Cl⁻)
mEq/L
Bicarbonate (HCO₃⁻)
mEq/L
Albumin — optional
g/dL

Result

Interpretation

Enter values above.

Notes & Sources

  • Potassium is excluded, which is the convention in most laboratories. If your institution includes K⁺, the normal range shifts upward by roughly 4 mEq/L.
  • Albumin correction matters. Albumin is the dominant unmeasured anion; each 1 g/dL fall lowers the measured gap by about 2.5 mEq/L. A hypoalbuminaemic patient can have a normal-looking gap while a genuine high-anion-gap acidosis is present.
  • The delta ratio is shown only when the corrected gap exceeds 12, and is used to detect a second, coexisting acid–base disorder.
  • Reference range used here: 8–12 mEq/L. Adjust to your own laboratory’s range.
Scroll to Top